Dr. Samina Yasmin

Assistant Professor, Chemistry
School of Science & Engineering
Email: samina.yasmin@sse.habib.edu.pk

Dr. Yasmin completed her D.Phil in the area of bio-inorganic chemistry from the Department of Chemistry at University of Oxford in 2006. Her research project demonstrated the chemistry of heme containing enzymes particularly focusing on a more difficult project of P450cam active site manipulations to target specific terpene substrates. This work constituted the first report of the oxidation of valencene to nootkatone by an engineered bacteria P450 enzyme and gained considerable attraction from both academia and industry because of its novelty.

Subsequently, she continued to pursue her research interests in biological chemistry in the School of Chemistry at University of East Anglia, UK starting from 2006 till the end of 2011. She had been working there in various capacities as a Senior Research Associate and Research Fellow on several projects, that involved a great deal of iron redox chemistry of biological system specifically to mention bacterioferritin with a particular focus to explore mechanism of iron mobilization from its iron mineral core.

Previously, at the beginning of her research career before even starting her Ph.D., She got an opportunity to work as Research Associate at National Institute for Biotechnology and Genetic Engineering (PAEC). Moreover, she was also enrolled with Quid-e-Azam University to pursue her MPhil in Biotechnology and completed her course work in 2002 prior to commence her Ph.D. at Oxford.

Education

  • Post-doc – Biological Chemistry, University of East Anglia, United Kingdom
  • Ph.D. – Biological Chemistry, University of Oxford, Oxford, United Kingdom
  • M.Sc. – Chemistry, University of Agriculture, Faisalabad, Pakistan
  • B.Sc. – Chemistry, Biology and Geography, Punjab University, Lahore, Pakistan

Awards and Honors

Dr. Yasmin is the recipient of the highly prestigious “Lady Noon Foundation Award” funded by Lady Noon Foundation and Chevening/British Council in 2002. Dr. Yasmin also acknowledges the scholarship awarded by Higher Education Commission of Pakistan in 2006 under the program “Partial Support for Ph.D. Studies Abroad”.

Research Interests

Dr. Yasmin has multi-disciplinary research interests ranging from general chemistry to protein chemistry, iron chemistry and enzyme kinetics to molecular biology. She has a wide range of experience in the fields of chemistry and biology which allows her to explore disciplines outside of chemistry as well. A long-term standing focus of her research would be to study project involving interesting chemistry combined with modern scientific biological applications.Ideally, it would be an advantageous to apply her expertise in collaboration with an appropriate experimental group both within Pakistan and abroad.

Dr. Yasmin is looking forward to reinforce the connection of chemistry within the context of liberal art education while bridging the theoretical tools and cutting edge chemical concepts with practical application through the establishment of instructional chemistry laboratory and curriculum at Habib University.

Selected Publications

  • Yasmin, S., Andrews, S. C., Moore, G. R. and Le Brun, N. E. (2011), A new role for heme: facilitating release of iron from the bacterioferritin iron biomineral. J.Biol. Chem. 286, 3473-3483.
  • Lawson TL, Crow A, Lewin A, Yasmin S, Moore GR, and Le Brun NE, “Monitoring the iron status of the ferroxidase centre ofEscherichia. coli  bacterioferritin using fluorescence spectroscopy” Biochemistry, 2009, Sep 29; 48(38):9031-9.
  • Swoden, R. J., Yasmin, S., Rees, N. H., Bell, S.G., and Wong L.L., (2005) “Biotransformation of the sesquiterpene (+)-valencene by P450cam and P450 BM3” Org. Biomol. Chem., 3, 57 – 64.
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